1. HORMONE PANELS
MEN
Total Testosterone
Measures total circulating testosterone.
Why it matters: Determines overall androgen status; low levels affect libido, muscle, fat loss, energy, mood.
Free Testosterone
Unbound, active testosterone.
Why it matters: More accurate predictor of symptoms than total T.
Bioavailable Testosterone
Portion available to tissues.
Why it matters: Helps determine if high SHBG is blocking testosterone utilization.
SHBG (Sex Hormone Binding Globulin)
Protein that binds hormones.
Why it matters: High SHBG → low usable testosterone; Low SHBG → metabolic issues.
Estradiol (E2 – Sensitive Assay)
Estrogen level in men.
Why it matters: Too high = mood swings, gyno; too low = joint pain, low libido.
DHEA-S
Precursor to sex hormones.
Why it matters: Declines with age; supports energy, mood, and androgen balance.
LH & FSH
Pituitary hormones stimulating testicles.
Why it matters: Distinguishes primary vs secondary hypogonadism.
Prolactin
Pituitary hormone.
Why it matters: High levels can suppress testosterone and libido.
Pregnenolone
Parent hormone for all steroid hormones.
Why it matters: Linked to memory, mood, stress response.
DHT (Dihydrotestosterone)
Potent androgen.
Why it matters: Controls libido, strength; too high may contribute to hair loss.
PSA (Prostate-Specific Antigen)
Prostate biomarker.
Why it matters: Required for safe TRT monitoring.
WOMEN
Estradiol (E2)
Primary female hormone.
Why it matters: Controls mood, metabolism, libido, menstrual cycle, bone health.
Progesterone
Key calming hormone.
Why it matters: Low levels → anxiety, PMS, infertility, sleep issues.
Total Testosterone
Overall androgen level.
Why it matters: Supports libido, strength, and energy.
Free Testosterone
Active testosterone.
Why it matters: More accurate for symptoms like low libido, fatigue, weight gain.
DHEA-S
Hormone precursor.
Why it matters: Anti-aging, improves mood, cognition, and adrenal function.
FSH / LH
Ovulation and ovarian function markers.
Why it matters: Critical for fertility and diagnosing hormonal imbalance.
Prolactin
Regulates menstrual cycle.
Why it matters: High levels → amenorrhea, infertility.
SHBG
Hormone binding protein.
Why it matters: High in women with low energy or under-eating; affects testosterone.
Pregnenolone
Neurosteroid precursor.
Why it matters: Supports cognition and stress resilience.
AMH (Anti-Müllerian Hormone)
Ovarian reserve marker.
Why it matters: Important for fertility, menopause prediction.
2. THYROID FUNCTION (MEN & WOMEN)
TSH (Thyroid Stimulating Hormone)
Master thyroid regulator.
Why it matters: Elevated levels suggest hypothyroidism; important for metabolism.
Free T3
Active thyroid hormone.
Why it matters: Low T3 = fatigue, weight gain, hair loss, slow metabolism.
Free T4
Thyroid hormone precursor.
Why it matters: Helps determine thyroid gland output.
Reverse T3 (rT3)
Inactive thyroid hormone.
Why it matters: High rT3 blocks T3 → common in chronic stress, dieting, illness.
TPO Antibodies
Autoimmune thyroid marker.
Why it matters: Detects Hashimoto’s disease before symptoms appear.
Thyroglobulin Antibodies (TgAb)
Another autoimmune thyroid marker.
Why it matters: Confirms autoimmune thyroid dysfunction.
3. METABOLIC & INSULIN SENSITIVITY MARKERS
Fasting Insulin
Shows insulin sensitivity.
Why it matters: Best early detector of prediabetes + weight-loss resistance.
Fasting Glucose
Blood sugar at baseline.
Why it matters: Elevated = metabolic dysfunction.
HbA1c
3-month blood sugar average.
Why it matters: Predicts diabetes risk.
C-Peptide
Insulin production indicator.
Why it matters: Helps identify insulin resistance vs insulin deficiency.
HOMA-IR
Insulin resistance index.
Why it matters: Strong predictor of metabolic disease.
ApoB (Apolipoprotein B)
Primary LDL particle marker.
Why it matters: BEST cardiovascular risk marker; better than LDL.
Lipoprotein(a)
Genetic cholesterol subtype.
Why it matters: Strong predictor of early heart disease.
4. INFLAMMATION & LONGEVITY MARKERS
hs-CRP (High Sensitivity C-Reactive Protein)
Systemic inflammation.
Why it matters: Higher levels → aging, heart disease, metabolic issues.
ESR (Sed Rate)
General inflammation marker.
Why it matters: Elevated in infections, autoimmune disorders.
Fibrinogen
Clotting protein.
Why it matters: Elevated levels raise stroke and heart attack risk.
Homocysteine
Amino acid affecting methylation.
Why it matters: High levels → cardiovascular risk + B vitamin deficiency.
Uric Acid
Metabolic waste product.
Why it matters: High levels = cardiovascular and metabolic risk.
Cortisol (AM/PM)
Stress hormone.
Why it matters: Chronic high cortisol → weight gain, burnout, aging acceleration.
5. LIVER, KIDNEY & DETOX MARKERS
Liver
AST / ALT
Liver cell enzymes.
Why it matters: Elevated from alcohol, fatty liver, medications, or toxicity.
Alkaline Phosphatase
Bile flow marker.
Why it matters: Indicates liver, bone, or gallbladder issues.
GGT
Oxidative stress toxin marker.
Why it matters: Top marker for alcohol damage and toxin load.
Bilirubin
Red blood cell breakdown.
Why it matters: Indicates liver and gallbladder health.
Kidney
Creatinine
Waste product filtered by kidneys.
Why it matters: Elevated = impaired kidney filtration.
BUN
Nitrogen waste product.
Why it matters: Helps assess hydration + kidney function.
eGFR
Overall kidney function.
Why it matters: Required to assess kidney disease risk.
6. LIPID & CARDIOVASCULAR MARKERS
Total Cholesterol
General lipid status.
Why it matters: Foundation of cardiovascular risk.
HDL
“Good” cholesterol.
Why it matters: Higher = protective.
LDL (Direct)
“Bad” cholesterol.
Why it matters: Helps risk-stratify; must be paired with ApoB.
Triglycerides
Blood fats.
Why it matters: High levels = metabolic dysfunction + insulin resistance.
VLDL
Very low density lipoproteins.
Why it matters: Linked to high triglycerides / liver issues.
LDL Particle Count (LDL-P)
Advanced lipoprotein marker.
Why it matters: More predictive of plaque formation.
7. NUTRIENT, ELECTROLYTE & MITOCHONDRIAL MARKERS
Vitamin D
Critical hormone-like vitamin.
Why it matters: Low = weak immunity, weight gain, depression.
Vitamin B12
Energy metabolism + nerves.
Why it matters: Deficiency → fatigue, neuropathy.
Folate (RBC Folate)
Methylation + DNA repair.
Why it matters: Essential for longevity + pregnancy.
Magnesium RBC
Intracellular magnesium.
Why it matters: Regulates energy, muscles, sleep, stress.
Iron Panel (Ferritin, Iron, TIBC, Transferrin Sat.)
Oxygen delivery.
Why it matters: Low iron → fatigue; high iron → inflammation, aging.
Zinc / Copper Ratio
Mineral balance.
Why it matters: Key for hormones, immunity, skin health.
CoQ10
Mitochondrial enzyme.
Why it matters: Essential for energy production; depleted by statins.
Omega-3 Index
EPA + DHA percentage.
Why it matters: Low levels = high inflammation + cardiovascular risk.
8. LONGEVITY & CELLULAR HEALTH
IGF-1
Growth hormone activity.
Why it matters: Low levels = aging; too high = cancer risk.
IGFBP-3
Binding protein.
Why it matters: Helps interpret GH status accurately.
Telomere Length
Genetic aging marker.
Why it matters: Short telomeres = accelerated aging.
NAD+/NADH Ratio
Cellular energy/repair marker.
Why it matters: Declines with age; correlated with mitochondrial health.
8-OHdG (Oxidative Stress)
DNA oxidation marker.
Why it matters: High levels = high oxidative aging.
9. REPRODUCTIVE MARKERS
Men
Semen Analysis
Fertility and testicular function.
FSH / LH
Determines sperm production health.
Prolactin
High levels suppress testosterone and fertility.
Women
AMH
Ovarian reserve.
FSH / LH
Cycle regularity + menopause transition.
Day-21 Progesterone
Ovulation confirmation.
10. SPECIALTY BIOHACKING ADD-ONS
Myokines (Irisin, Myostatin)
Muscle signaling proteins.
Why it matters: Myostatin inhibits muscle growth; Irisin boosts fat burning.
Adiponectin / Leptin
Metabolic hormones.
Why it matters: Regulate weight, appetite, insulin sensitivity.
Gut Microbiome Panel
Gut ecosystem.
Why it matters: Impacts immunity, mood, weight, inflammation.
Heavy Metals
Toxins like mercury, lead.
Why it matters: Causes fatigue, hormonal imbalance, aging.
Mold/Mycotoxin Panel
Environmental toxins.
Why it matters: A cause of fatigue, hormonal issues, inflammation.